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Locomotor activity of rats after stimulation of the nucleus locus coeruleus region or after lesion of the dorsal noradrenergic bundle: effects of clonidine, prazosin and yohimbine.

作者信息

Velley L, Kempf E, Cardo B

出版信息

Psychopharmacology (Berl). 1982;78(3):239-44. doi: 10.1007/BF00428158.

DOI:10.1007/BF00428158
PMID:6296900
Abstract
摘要

相似文献

1
Locomotor activity of rats after stimulation of the nucleus locus coeruleus region or after lesion of the dorsal noradrenergic bundle: effects of clonidine, prazosin and yohimbine.刺激大鼠蓝斑核区域或损毁背侧去甲肾上腺素能束后的运动活动：可乐定、哌唑嗪和育亨宾的作用。
Psychopharmacology (Berl). 1982;78(3):239-44. doi: 10.1007/BF00428158.
2
Evidence that locus coeruleus is the site where clonidine and drugs acting at alpha 1- and alpha 2-adrenoceptors affect sleep and arousal mechanisms.有证据表明，蓝斑是可乐定及作用于α1和α2肾上腺素能受体的药物影响睡眠和觉醒机制的部位。
Br J Pharmacol. 1987 Apr;90(4):675-85. doi: 10.1111/j.1476-5381.1987.tb11220.x.
3
Modulation of rat brain alpha- and beta-adrenergic receptor populations by lesion of the dorsal noradrenergic bundle.通过损毁背侧去甲肾上腺素能束对大鼠脑α和β肾上腺素能受体群体的调节
Brain Res. 1980 Apr 7;187(1):143-54. doi: 10.1016/0006-8993(80)90500-4.
4
Differential blocking effects of prazosin and yohimbine on vasopressor responses to sympathetic nerve stimulation and intravenous norepinephrine in the pithed rat.哌唑嗪和育亨宾对去脑大鼠交感神经刺激和静脉注射去甲肾上腺素引起的升压反应的不同阻断作用。
Res Commun Chem Pathol Pharmacol. 1984 Jan;43(1):97-112.
5
Concomitant depression of locus coeruleus neurons and of flexor reflexes by an alpha 2-adrenergic agonist in rats: a possible mechanism for an alpha 2-mediated muscle relaxation.
Neuroscience. 1990;34(1):177-87. doi: 10.1016/0306-4522(90)90311-q.
6
Facilitation of learning consecutive to electrical stimulation of the locus coeruleus: cognitive alteration or stress-reduction?蓝斑核电刺激后对学习的促进作用：认知改变还是应激减轻？
Prog Brain Res. 1991;88:555-69. doi: 10.1016/s0079-6123(08)63834-0.
7
Activation of lateral geniculate neurons by locus coeruleus or dorsal noradrenergic bundle stimulation: selective blockade by the alpha 1-adrenoceptor antagonist prazosin.蓝斑或背侧去甲肾上腺素能束刺激对外侧膝状体神经元的激活：α1肾上腺素能受体拮抗剂哌唑嗪的选择性阻断作用
Brain Res. 1982 Oct 28;250(1):31-9. doi: 10.1016/0006-8993(82)90950-7.
8
Behavioural and electrocortical spectrum-power effects of clonidine and related drugs given into several areas of the rat brain.可乐定及相关药物注入大鼠脑内多个区域后的行为和皮层电图频谱功率效应。
Ann Ist Super Sanita. 1988;24(3):421-8.
9
alpha-methyldopa reduces locomotor activity in rats via its metabolite, alpha-methylnorepinephrine, acting on alpha 2-adrenoceptors.α-甲基多巴通过其代谢产物α-甲基去甲肾上腺素作用于α2-肾上腺素能受体，从而降低大鼠的运动活性。
Arch Int Pharmacodyn Ther. 1980 Apr;244(2):231-43.
10
Clonidine causes antidepressant-like effects in rats by activating alpha 2-adrenoceptors outside the locus coeruleus.
Eur J Pharmacol. 1991 Feb 14;193(3):309-13. doi: 10.1016/0014-2999(91)90144-f.

引用本文的文献

1
The pharmacological stressor yohimbine, but not U50,488, increases responding for conditioned reinforcers paired with ethanol or sucrose.药理应激剂育亨宾，而不是 U50,488，会增加与乙醇或蔗糖配对的条件性强化物的反应。
Psychopharmacology (Berl). 2020 Dec;237(12):3689-3702. doi: 10.1007/s00213-020-05647-0. Epub 2020 Aug 25.
2
Noradrenergic hyperactivity in hippocampus after partial denervation: pharmacological, behavioral, and electrophysiological studies.部分去神经支配后海马中去甲肾上腺素能功能亢进：药理学、行为学及电生理学研究
Exp Brain Res. 1994;99(2):259-66. doi: 10.1007/BF00239592.
3
Clonidine and a beta-agonists induce hyperthermia in rats at high ambient temperature.

本文引用的文献

1
Improved technique for the fluorimetric estimation of catecholamines.儿茶酚胺荧光测定的改进技术。
Acta Physiol Scand. 1961 Apr;51:348-55. doi: 10.1111/j.1748-1716.1961.tb02128.x.
2
Clonidine: attenuation of sedative action by facilitated central noradrenergic neurotransmission.可乐定：通过促进中枢去甲肾上腺素能神经传递减弱镇静作用。
J Neural Transm. 1980;47(1):29-39. doi: 10.1007/BF01256637.
3
Pre- and postsynaptic alpha adrenoceptor selectivity studies with yohimbine and its two diastereoisomers rauwolscine and corynanthine in the anesthetized dog.
可乐定和β-激动剂在高环境温度下可使大鼠体温升高。
J Neural Transm. 1985;63(3-4):223-35. doi: 10.1007/BF01252027.
在麻醉犬中使用育亨宾及其两种非对映异构体萝芙辛和柯楠碱进行突触前和突触后α肾上腺素能受体选择性研究。
J Pharmacol Exp Ther. 1981 Nov;219(2):540-6.
4
alpha 1- and alpha 2-adrenoceptors in rat cerebral cortex: effect of frontal lobotomy.
Naunyn Schmiedebergs Arch Pharmacol. 1981 Feb;316(1):42-4. doi: 10.1007/BF00507225.
5
Modulation of rat brain alpha-adrenoreceptor populations four weeks after stimulation of the nucleus locus coeruleus.蓝斑核刺激四周后大鼠脑α-肾上腺素能受体群体的调节
Psychopharmacology (Berl). 1981;74(3):226-31. doi: 10.1007/BF00427099.
6
The pharmacology of prazosin, a novel antihypertensive agent.新型抗高血压药物哌唑嗪的药理学
Life Sci. 1980 Oct 27;27(17):1525-40. doi: 10.1016/0024-3205(80)90561-5.
7
alpha-methyldopa reduces locomotor activity in rats via its metabolite, alpha-methylnorepinephrine, acting on alpha 2-adrenoceptors.α-甲基多巴通过其代谢产物α-甲基去甲肾上腺素作用于α2-肾上腺素能受体，从而降低大鼠的运动活性。
Arch Int Pharmacodyn Ther. 1980 Apr;244(2):231-43.
8
3H-Prazosin binds specifically to 'alpha 1'-adrenoceptors in rat brain.3H-哌唑嗪特异性结合大鼠脑中的“α1”肾上腺素能受体。
Naunyn Schmiedebergs Arch Pharmacol. 1980 May;312(1):23-6. doi: 10.1007/BF00502569.
9
Radioligand binding studies of adrenergic receptors: new insights into molecular and physiological regulation.肾上腺素能受体的放射性配体结合研究：对分子和生理调节的新见解
Annu Rev Pharmacol Toxicol. 1980;20:581-608. doi: 10.1146/annurev.pa.20.040180.003053.
10
Modulation of rat brain alpha- and beta-adrenergic receptor populations by lesion of the dorsal noradrenergic bundle.通过损毁背侧去甲肾上腺素能束对大鼠脑α和β肾上腺素能受体群体的调节
Brain Res. 1980 Apr 7;187(1):143-54. doi: 10.1016/0006-8993(80)90500-4.