Bonneterre J, Peyrat J P, Vandewalle B, Beuscart R, Vie M C, Cappelaere P
Eur J Cancer Clin Oncol. 1982 Nov;18(11):1157-62. doi: 10.1016/0277-5379(82)90097-9.
Prolactin receptors have been measured in 92 human breast carcinomas. Both free and total receptors (after desaturation by MgCl2) have been looked for. Free receptors have been found in 46% of the cases, total receptors in 72%. Specific binding ranges from 0.8 to 8.0%. No correlation could be found between prolactin receptors and age, weight, menopausal status and pathological features (differentiation, histoprognostic grading, cellular density). A highly significant correlation has been found between prolactin receptors on the one hand and estradiol and progesterone receptors on the other.
已对92例人类乳腺癌进行了催乳素受体检测。同时检测了游离受体和总受体（用MgCl₂去饱和后）。46%的病例中发现有游离受体，72%的病例中有总受体。特异性结合范围为0.8%至8.0%。未发现催乳素受体与年龄、体重、绝经状态及病理特征（分化程度、组织预后分级、细胞密度）之间存在相关性。但发现催乳素受体一方面与雌二醇受体，另一方面与孕酮受体之间存在高度显著的相关性。
