Fridrikh F, Borkhardt U
Zh Vopr Neirokhir Im N N Burdenko. 1982 Nov-Dec(6):27-32.
The results of operations performed on 126 patients for adenoma of the hypophysis from 1954 to 1975 by the transfrontal approach are analysed. In most patients the adenoma was marked by suprasellar growth. The clinical symptoms and the specific features of the methods of examination and surgical treatment are described. Postoperative mortality was 18.2%, duration of catamnestic follow-up 5-10 years. Recurrences were found in 14% of cases. They occurred 5-8 years, on the average, after the first operation and 1.3 years after repeated operations. The necessity of early diagnosis of hypophyseal adenoma is emphasized. Modified operative techniques and substitution hormonal therapy in combination with timely diagnosis are decisive in improving the results of treatment of patients with adenoma of the hypophysis.
分析了1954年至1975年间采用经额入路对126例垂体腺瘤患者进行手术的结果。大多数患者的腺瘤表现为鞍上生长。描述了临床症状以及检查和手术治疗方法的具体特点。术后死亡率为18.2%，随访期为5至10年。14%的病例出现复发。复发平均发生在首次手术后5至8年，再次手术后1.3年。强调了早期诊断垂体腺瘤的必要性。改良手术技术和替代激素治疗与及时诊断相结合，对于改善垂体腺瘤患者的治疗效果具有决定性作用。
