人类白细胞抗原与滋养层疾病
HLA and trophoblastic disease.
作者信息
Law H Y
出版信息
Ann Acad Med Singap. 1982 Oct;11(4):549-54.
PMID:6299166
Abstract
The susceptibility of trophoblastic diseases is not associated with HLA antigens. Compatibility studies between the patient and her husband, and the patient and the tumour suggest that it may not play an important role in the susceptibility or the progression of the tumour. This as well as other direct evidence indicate that the tumour cells probably do not express much HLA antigens on their cell surface. The expression of HLA antigens on normal and abnormal trophoblasts are discussed.
摘要
滋养层疾病的易感性与HLA抗原无关。患者与其丈夫以及患者与肿瘤之间的相容性研究表明，HLA抗原可能在肿瘤的易感性或进展中不起重要作用。这一点以及其他直接证据表明，肿瘤细胞表面可能没有大量表达HLA抗原。本文还讨论了正常和异常滋养层细胞上HLA抗原的表达情况。
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