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两性霉素B、咪康唑和酮康唑对人粒细胞祖细胞的体外毒性。

Toxicity of amphotericin B, miconazole, and ketoconazole to human granulocyte progenitor cells in vitro.

作者信息

Meeker T C, Siegel M S, Shiota F M, Crowley J J, McGuffin R W

出版信息

Antimicrob Agents Chemother. 1983 Jan;23(1):169-71. doi: 10.1128/AAC.23.1.169.

Abstract

Granulocyte progenitor cells were grown in culture with amphotericin B, miconazole, and ketoconazole. Significant suppression of progenitor cell growth could be demonstrated with all three drugs at increasing concentrations. No additive suppression was seen when amphotericin B and ketoconazole were combined.

摘要

粒细胞祖细胞在含有两性霉素B、咪康唑和酮康唑的培养基中培养。随着三种药物浓度的增加,均可证明祖细胞生长受到显著抑制。当两性霉素B和酮康唑联合使用时,未见相加抑制作用。

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