Badaeva L N, Ovsiannikova L M, Kruk V I
Arkh Anat Gistol Embriol. 1982 Dec;83(12):59-64.
When pregnant rats are administered chlororganic pesticide dilor, certain ultrastructural changes are observed in neurocytes and in myelin fibers, in the spinal cord, that demonstrates some disorders in cellular and tissue metabolism. In the newborn spinal cords a retarded differentiation is observed against the background of an intense cellular metabolism. By means of the electron paramagnetic resonance technique, an increasing concentration of free radicals in the brains and spinal cords of the pregnant animals and in their one-month-old offsprings is demonstrated. The investigation on fatty acid composition of lipids in pregnant test animals demonstrates a decrease in cholysterine, steroids and some fatty acids in myelin fractions and in synaptosomic membranes.
当给怀孕大鼠施用有机氯农药敌敌涕时，在脊髓的神经细胞和髓鞘纤维中会观察到某些超微结构变化，这表明细胞和组织代谢存在一些紊乱。在新生脊髓中，在强烈的细胞代谢背景下观察到分化延迟。通过电子顺磁共振技术，证明怀孕动物及其1个月大的后代的大脑和脊髓中自由基浓度增加。对怀孕实验动物脂质脂肪酸组成的研究表明，髓磷脂组分和突触体膜中的胆固醇、类固醇和一些脂肪酸减少。
