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角膜巩膜纤维组织细胞瘤

Fibrous histiocytoma of the corneosclera.

作者信息

Litriĉin O

出版信息

Arch Ophthalmol. 1983 Mar;101(3):426-8. doi: 10.1001/archopht.1983.01040010426017.

DOI:10.1001/archopht.1983.01040010426017
PMID:6299256
Abstract

A 65-year-old woman had a slowly progressive sclerocorneal lesion that, after three years of unsuccessful medical treatment, involved almost the whole cornea and the surrounding sclera in the temporal lower quadrant. The tumor had a nodular surface. During the next two years, the tumor was operated on four times (twice by keratectomy and twice by lamellar sclerokeratoplasty). Microscopic examination revealed a fibrous histiocytoma. The resection was histologically incomplete on all occasions. Five years after the onset of the disease, the eye was enucleated. A spontaneous invasion of the iris could not be diagnosed with certainty, because there was a perforation at the limbus during a preceding operation.

摘要

一名65岁女性患有缓慢进展的角膜巩膜病变,经过三年的药物治疗无效后,病变几乎累及整个角膜以及颞下象限的周边巩膜。肿瘤表面呈结节状。在接下来的两年里,该肿瘤接受了4次手术(2次角膜切除术和2次板层角膜巩膜成形术)。显微镜检查显示为纤维组织细胞瘤。每次手术切除在组织学上均不完全。疾病发作五年后,该眼被摘除。由于之前的一次手术中角膜缘出现穿孔,无法确切诊断虹膜是否发生自发浸润。

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引用本文的文献

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Successful treatment of recurrent benign fibrous histiocytoma by complete surgical removal and appropriate ocular surface reconstruction: A case report.通过完整手术切除和适当的眼表重建成功治疗复发性良性纤维组织细胞瘤:一例报告。
Medicine (Baltimore). 2020 Oct 30;99(44):e22941. doi: 10.1097/MD.0000000000022941.
2
The epidemiology, clinical characteristics, histopathology and management of juvenile- and adult-onset corneoscleral limbus xanthogranuloma.青少年及成人期角膜缘黄色瘤的流行病学、临床特征、组织病理学及治疗
Graefes Arch Clin Exp Ophthalmol. 2016 Mar;254(3):413-20. doi: 10.1007/s00417-015-3261-2. Epub 2016 Jan 21.
3
Management of fibrous histiocytoma of the corneoscleral limbus: report of a case and review of the literature.
角膜缘纤维组织细胞瘤的治疗:1例报告并文献复习
Graefes Arch Clin Exp Ophthalmol. 1997 Feb;235(2):87-91. doi: 10.1007/BF00941735.
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Adult limbal xanthogranuloma.成人角膜缘黄色瘤
Br J Ophthalmol. 1984 May;68(5):360-3. doi: 10.1136/bjo.68.5.360.
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Ocular malignant fibrous histiocytoma: clinical and histopathological characteristics.眼部恶性纤维组织细胞瘤:临床及组织病理学特征
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Malignant fibrous histiocytoma of the conjunctiva.结膜恶性纤维组织细胞瘤
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