Identification and characterization of Epstein-Barr virus-related surface polypeptides expressed on n-butyrate-treated P3HR-1 cells.

Seven polypeptides [300,000 (300K), 250K, 150K, 140K, 120K, 87K and 52K] were identified as Epstein-Barr virus(EBV)-related surface polypeptides expressed on n-butyrate-treated P3HR-1 cells. Five polypeptides (300K, 250K, 150K, 120K and 87K) were sensitive to phosphonoacetic acid, and four of these (300K, 250K, 120K and 87K) were glycoproteins. The 300K and 250K polypeptides had a slightly higher molecular size and the 87K polypeptide a slightly lower molecular size than the corresponding polypeptides detected in virus-producing P3HR-1 cells and in the envelope of EBV particles.