DeVries G H, Chalifour R J, Kanfer J N
J Neurochem. 1983 Apr;40(4):1189-91. doi: 10.1111/j.1471-4159.1983.tb08114.x.
An axolemma-enriched fraction prepared from a purified myelinated axon fraction isolated from rat CNS was found to contain phospholipase D at a specific activity similar to that of a microsomal fraction isolated from whole brain. There was a concomitant threefold enrichment in the specific activity of phospholipase D and acetylcholinesterase in the axolemma-enriched fraction compared with the specific activities of these enzymes in the starting white matter whole homogenate. This axonal phospholipase D may be involved in remodeling of phospholipid, which in turn may affect axonal functions such as ion translocation.
从大鼠中枢神经系统分离得到的纯化有髓轴突部分制备的富含轴膜的部分，被发现含有磷脂酶D，其比活性与从全脑分离得到的微粒体部分相似。与起始白质全匀浆中这些酶的比活性相比，富含轴膜的部分中磷脂酶D和乙酰胆碱酯酶的比活性同时提高了三倍。这种轴突磷脂酶D可能参与磷脂的重塑，进而可能影响轴突功能，如离子转运。
