Goffman T E, Woo S Y, Manz H, McCullough D, Sinks L F, Chun B K, Miller R W
Med Pediatr Oncol. 1983;11(2):130-3. doi: 10.1002/mpo.2950110212.
A 5-year-old boy developed an ependymoma; 3 years later, after chemotherapy and radiotherapy, he developed glioblastoma multiforme and acute myeloblastic leukemia. His maternal grandmother had died at a young age of colon cancer. Since ependymoma is not known to predispose to other cancers, the unusual sequence of malignant disease may have been due to combined therapy in a susceptible host.
一名5岁男孩患了室管膜瘤;3年后,在化疗和放疗后,他又患上了多形性胶质母细胞瘤和急性髓细胞白血病。他的外祖母年轻时死于结肠癌。由于室管膜瘤一般不会引发其他癌症,这种不寻常的恶性疾病序列可能是由于在一个易患癌症的宿主身上进行了联合治疗。