远距致癌物对3T3细胞的12-O-十四烷酰佛波醇-13-乙酸酯非增殖变体无促有丝分裂作用。
Teleocidin is not mitogenic for 12-O-tetradecanoylphorbol-13-acetate non-proliferative variants of 3T3 cells.
作者信息
Herschman H R
出版信息
Carcinogenesis. 1983;4(4):489-90. doi: 10.1093/carcin/4.4.489.
PMID:6301704
Abstract
Teleocidin and 12-O-tetradecanoylphorbol-acetate (TPA), two potent tumor promoters, are also excellent mitogens for 3T3 cells. I now demonstrate that teleocidin is unable to stimulate mitogenesis in TPA non-proliferative 3T3 variants that retain TPA receptors.
摘要
远距致癌物和十四酰佛波醇乙酸酯（TPA）这两种强效肿瘤促进剂，也是3T3细胞的优良促细胞分裂剂。我现在证明，远距致癌物无法在保留TPA受体的TPA非增殖性3T3变体中刺激有丝分裂。
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