Pagès M, Pagès A M
Sem Hop. 1983 Mar 3;59(9):610-6.
Muscle biopsies from 13 patients with polymyositis were studied with light microscopy, histoenzymology and electron microscopy. Light microscopy often shows degenerative muscle fibers and endomysial collections of inflammatory cells. These findings are helpful for the diagnosis but are not consistent. Histoenzymology may other features such as perifascicular atrophy, and alterations in cytoplasmic staining patterns, but these changes are non specific. Electron microscopy frequently reveals vascular changes, especially pseudoviral inclusions, which are the most reliable factors and the most frequently observed changes in ultrastructural diagnosis.
对13例多发性肌炎患者的肌肉活检标本进行了光镜、组织酶学和电镜研究。光镜下常可见变性的肌纤维和肌内膜炎症细胞浸润。这些发现有助于诊断，但并不一致。组织酶学检查可能发现其他特征，如束周萎缩和细胞质染色模式改变，但这些变化不具有特异性。电镜检查常可发现血管改变，尤其是假病毒包涵体，这是超微结构诊断中最可靠、最常观察到的变化。
