Regulation of human placental deoxyguanosine kinase by nucleotides.
作者信息
Yamada Y, Goto H, Ogasawara N
出版信息
FEBS Lett. 1983 Jun 27;157(1):51-3. doi: 10.1016/0014-5793(83)81114-4.
PMID:6305717
Abstract
The activity of deoxyguanosine kinase purified from human placenta was regulated by various nucleotides. dTTP, an activator, only increased the Vmax value of the enzyme. The feedback inhibition by dGTP, dGDP and dGMP were competitive with respect to deoxyguanosine. Both the activation by dTTP and the inhibition by dGTP were reversible.
摘要
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