文献检索，用中文搜 PubMed

Suppr 超能文献

核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Moutafchiev D A, Shisheva A C, Sirakov L M

Int J Biochem. 1983;15(5):755-8. doi: 10.1016/0020-711x(83)90205-7.

Cells isolated from a lactating rabbit mammary gland have been investigated for transferrin-iron receptors. The existence of these structures has been demonstrated through a specific binding with a competitor non-labelled rabbit transferrin. 2. The interaction of iron-receptor complex depends on the concentration of [59Fe]transferrin, the number of cells and the time. 3. Scatchard's plot of data indicates two classes of receptor sites: one with a binding capacity 6.48 x 10(-9) g Fe per cell and affinity constant 2.48 x 10(10) M-1 and another with 1.06 x 10(-8) g Fe per cell and 4.66 x 10(11) M-1 respectively. 4. The probable mechanism of the iron transport from blood to milk through the lactating cell was discussed.

已对从泌乳兔乳腺分离出的细胞进行转铁蛋白 - 铁受体研究。通过与未标记的竞争兔转铁蛋白特异性结合，证实了这些结构的存在。2. 铁 - 受体复合物的相互作用取决于[59Fe]转铁蛋白的浓度、细胞数量和时间。3. 数据的Scatchard图表明有两类受体位点：一类每个细胞的结合容量为6.48×10(-9) g铁，亲和常数为2.48×10(10) M-1；另一类每个细胞为1.06×10(-8) g铁，亲和常数为4.66×10(11) M-1。4. 讨论了铁通过泌乳细胞从血液转运到乳汁的可能机制。

Moutafchiev D A, Shisheva A C, Sirakov L M

Int J Biochem. 1983;15(5):755-8. doi: 10.1016/0020-711x(83)90205-7.

Cells isolated from a lactating rabbit mammary gland have been investigated for transferrin-iron receptors. The existence of these structures has been demonstrated through a specific binding with a competitor non-labelled rabbit transferrin. 2. The interaction of iron-receptor complex depends on the concentration of [59Fe]transferrin, the number of cells and the time. 3. Scatchard's plot of data indicates two classes of receptor sites: one with a binding capacity 6.48 x 10(-9) g Fe per cell and affinity constant 2.48 x 10(10) M-1 and another with 1.06 x 10(-8) g Fe per cell and 4.66 x 10(11) M-1 respectively. 4. The probable mechanism of the iron transport from blood to milk through the lactating cell was discussed.

已对从泌乳兔乳腺分离出的细胞进行转铁蛋白 - 铁受体研究。通过与未标记的竞争兔转铁蛋白特异性结合，证实了这些结构的存在。2. 铁 - 受体复合物的相互作用取决于[59Fe]转铁蛋白的浓度、细胞数量和时间。3. 数据的Scatchard图表明有两类受体位点：一类每个细胞的结合容量为6.48×10(-9) g铁，亲和常数为2.48×10(10) M-1；另一类每个细胞为1.06×10(-8) g铁，亲和常数为4.66×10(11) M-1。4. 讨论了铁通过泌乳细胞从血液转运到乳汁的可能机制。