Fukuzawa T, Ide H
J Exp Zool. 1983 May;226(2):239-44. doi: 10.1002/jez.1402260209.
Melanophores of wild-type and periodic albino mutants of Xenopus laevis were successfully cultured in vitro. They proliferated in the presence of alpha-melanocyte-stimulating hormone (alpha-MSH or cyclic adenosine monophosphate (cAMP) at a doubling time of 8-10 days. These proliferating melanophores retained their phenotypes, ability to synthesize melanin, and melanin-dispersing response to MSH stimulation. Neither depigmentation nor selective cell death of periodic albino melanophores was observed for at least 4 months during the cultivation.
非洲爪蟾野生型和周期性白化突变体的黑素细胞成功地在体外培养。它们在α-黑素细胞刺激素（α-MSH）或环磷酸腺苷（cAMP）存在的情况下增殖，倍增时间为8至10天。这些增殖的黑素细胞保留了它们的表型、合成黑色素的能力以及对MSH刺激的黑色素分散反应。在培养过程中，至少4个月未观察到周期性白化黑素细胞的色素脱失或选择性细胞死亡。
