Winston D J, Kurtz T O, Fleischmann J, Morgan D, Batzdorf U, Stern W E
J Neurosurg. 1983 Aug;59(2):328-31. doi: 10.3171/jns.1983.59.2.0328.
An unusual case is reported of a patient with spastic paraparesis who was found to have severe spinal arachnoiditis due to Coccidioides immitis. Despite an obstructive hydrocephalus and a spinal subarachnoid block, the patient was treated effectively with surgery (shunting) and antifungal therapy (amphotericin and ketoconazole). He remains asymptomatic 3 years after diagnosis. Aggressive surgical and medical treatment of coccidioidal infection of the central nervous system can be beneficial, even in patients with the worst prognosis.