Adeyokunnu A A
Afr J Med Med Sci. 1982 Sep;11(3):105-12.
A study of 22 769 consecutive live births in a Nigerian hospital has revealed the incidence of Turner's syndrome to be 1 in 2745 live females. Shortness of stature and neck, low posterior hair line, broad chest with widely spaced rudimentary nipples, congenital lymphoedema, redundant lax neck skin and hypoplastic nails were the most common clinical features. Birth weight was above 2.5 kg in only five of the fourteen cases in which this measurement was taken. Associated renal and cardiovascular anomalies occurred in 87.5 and 45% of the cases respectively. While neither parental age nor the birth rank of the patients were contributory factors in the causation of the syndrome, ingestion of traditional medicinal concoctions during the pregnancy which appeared to have played a role in four out of the sixteen cases requires further studies.
一项对尼日利亚一家医院连续22769例活产病例的研究显示,特纳综合征在活产女性中的发病率为1/2745。身材矮小、颈部短小、后发际线低、胸部宽阔且乳头发育不全且间距宽、先天性淋巴水肿、颈部皮肤松弛多余以及指甲发育不全是最常见的临床特征。在测量出生体重的14例病例中,只有5例出生体重超过2.5千克。相关的肾脏和心血管异常分别发生在87.5%和45%的病例中。虽然父母年龄和患者的出生顺序都不是该综合征病因的促成因素,但在16例病例中有4例,孕期摄入传统草药似乎起到了一定作用,这需要进一步研究。