Penton Z, Bissell G
Clin Chem. 1978 Mar;24(3):504-6.
Bovine blood is used frequently as control material in interlaboratory comparisons for blood-lead analysis, but an erythrocyte protoporphyrin control material is needed. We present data on the rate of changes in blood lead and erythrocyte protoporphyrin in steers fed lead acetate. We also show, by comparison of fluorescence spectra with those of known compounds, that most of the porphyrin in lead-burdened steers probably exists as free protoporphyrin IX along with some zinc-complexed protoporphyrin IX. Bovine blood is suitable as an erythrocyte protoporphyrin control material for laboratories using acid extraction procedures, but not for the proficiency testing of laboratories using hematofluorometers.
牛血常被用作血铅分析实验室间比对的对照材料，但需要一种红细胞原卟啉对照材料。我们给出了给公牛饲喂醋酸铅后血铅和红细胞原卟啉的变化率数据。通过将荧光光谱与已知化合物的荧光光谱进行比较，我们还表明，铅负荷公牛体内的大部分卟啉可能以游离原卟啉IX的形式存在，同时还有一些锌络合原卟啉IX。牛血适合作为采用酸提取程序的实验室的红细胞原卟啉对照材料，但不适合用于采用血液荧光计的实验室的能力验证。
