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A small animal model study of perlite and fir bark dust on guinea pig lungs.

作者信息

McMichael R F, DiPalma J R, Blumenstein R, Amenta P S, Freedman A P, Barbieri E J

出版信息

J Pharmacol Methods. 1983 May;9(3):209-17. doi: 10.1016/0160-5402(83)90040-2.

DOI:10.1016/0160-5402(83)90040-2
PMID:6308352
Abstract

Fir bark (Abies) and perlite (noncrystalline silicate) dusts have been reported to cause pulmonary disease in humans. Guinea pigs were exposed to either fir bark or perlite dust in a special chamber. Severe pathologic changes occurred in the lungs, consisting of lymphoid aggregated and a perivascular inflammatory response. Both dusts caused similar changes although one was vegetable (fir bark) and the other mineral (perlite). Fir bark and perlite dust appeared to be more than just nuisance dusts.

摘要

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引用本文的文献

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Int J Environ Res Public Health. 2013 Oct 14;10(10):4982-95. doi: 10.3390/ijerph10104982.