Denck H, Sponer D
Langenbecks Arch Chir. 1976 Nov 15;342:173-9. doi: 10.1007/BF01267365.
As long-term results of portosystemic shunt operations for decompression of the portal hypertension are unsatisfactory, the author's therapeutic trials are directed increasingly at local treatment of varicosity. One treatment used is esophagoscopic submucosal sclerosing therapy of the esophageal wall for detachment of the varices from the surface. This method proved to be of great value in 420 patients, as the incidence of fatal recurrences of bleeding was only 12% and primary mortality was 15%. Suggested indications for endoscopic mural sclerosing are discussed. Mural sclerosing associated with transhepatic percutaneous esophageal varix sclerosis (following Lunderquist) might improve the results further in some cases.
由于门静脉高压减压的门体分流手术长期效果不尽人意，作者的治疗试验越来越多地针对静脉曲张的局部治疗。一种治疗方法是通过食管镜对食管壁进行黏膜下硬化治疗，使静脉曲张从表面脱离。该方法在420例患者中显示出巨大价值，因为致命性出血复发率仅为12%，初次死亡率为15%。文中讨论了内镜下壁内硬化治疗的建议适应证。在某些情况下，壁内硬化治疗联合经皮肝穿刺食管静脉曲张硬化治疗（遵循伦德奎斯特法）可能会进一步改善治疗效果。
