Pittman Q J
Neurosci Lett. 1983 Jun 30;37(3):239-43. doi: 10.1016/0304-3940(83)90437-8.
Antidromic action potentials were recorded from rat paraventricular nucleus (PVN) and supraoptic nucleus neurons following electrical stimulation of the pituitary stalk. Increases in stimulation frequency to 10 or 20 Hz caused progressive increases in antidromic latency and, often, failure of the antidromic potential within 1 min. Similar changes were observed in antidromically invaded PVN neurons in a hypothalamic slice; this condition could be mimicked at 1 Hz stimulation when the potassium concentration was increased in the perfusate. These results suggest that the ionic environment of axons can influence their ability to transmit impulses.
在对垂体柄进行电刺激后，从大鼠室旁核（PVN）和视上核神经元记录到了逆向动作电位。将刺激频率增加到10或20赫兹会导致逆向潜伏期逐渐延长，并且常常在1分钟内逆向电位消失。在下丘脑切片中逆向侵入的PVN神经元中也观察到了类似变化；当灌流液中的钾浓度增加时，在1赫兹刺激下也可模拟出这种情况。这些结果表明轴突的离子环境会影响其传递冲动的能力。
