Pohjavuori M, Fyhrquist F
Acta Paediatr Scand Suppl. 1983;305:79-83. doi: 10.1111/j.1651-2227.1983.tb09865.x.
In 21 normal deliveries, high concentrations of AVP and ACTH in cord blood were associated with higher blood pressure and lower skin temperature, indicating peripheral vasoconstriction. Following Caesarean section after the onset of labour (n = 8), cord AVP concentrations and blood pressures were lower than after normal delivery but higher than after elective Caesarean section (n = 9). Maternal AVP concentrations at delivery were normal, as were plasma AVP concentrations in all infants 3 days after delivery. The relationship between vasopressin, a potential ACTH releasing factor, and ACTH was interesting. We conclude that the massive release of vasopressin is associated with normal delivery, elevated ACTH values and with peripheral vasoconstriction. These findings reflect favourable adaptation to hypoxia and stress of delivery, intended to redistribute cardiac output to vital organs and may provide for physiological adjustments necessary for extrauterine life.
在21例正常分娩中，脐血中高浓度的抗利尿激素（AVP）和促肾上腺皮质激素（ACTH）与较高的血压及较低的皮肤温度相关，提示外周血管收缩。在临产发动后行剖宫产的产妇中（n = 8），脐血AVP浓度及血压低于正常分娩后，但高于择期剖宫产术后（n = 9）。分娩时母体的AVP浓度正常，所有婴儿出生3天后的血浆AVP浓度也正常。血管加压素（一种潜在的促肾上腺皮质激素释放因子）与促肾上腺皮质激素之间的关系很有意思。我们得出结论，血管加压素的大量释放与正常分娩、升高的促肾上腺皮质激素值及外周血管收缩有关。这些发现反映了对分娩时缺氧和应激的良好适应，旨在将心输出量重新分配至重要器官，并可能为宫外生活提供必要的生理调节。
