Bablanian G M, Treistman S N
Brain Res. 1983 Jul 25;271(2):342-5. doi: 10.1016/0006-8993(83)90298-6.
Activity in cell R15 was monitored in a preparation of Aplysia californica in which all sensory inputs and the hemolymph were left intact. R15 exhibited bursting pacemaker activity in situ. Substitution of 93% sea water for normal sea water produced a hyperpolarization of R15 which either silenced the cell or significantly increased the interburst interval in 9 out of 12 of the experiments. Excitatory activity from head ganglia acted to antagonize this inhibitory response. The results provide support for a role of R15 in osmoregulation, and provide a model system in which the interaction of an identified neurosecretory cell, peptide release, and physiological response may be studied.
在一种加州海兔的标本中监测了R15细胞的活动，该标本中所有感觉输入和血淋巴均保持完整。R15在原位表现出爆发性起搏活动。用93%的海水替代正常海水会使R15发生超极化，在12个实验中的9个实验中，这要么使细胞沉默，要么显著增加爆发间期。来自头部神经节的兴奋性活动起到对抗这种抑制反应的作用。这些结果支持了R15在渗透调节中的作用，并提供了一个模型系统，在其中可以研究一个已确定的神经分泌细胞、肽释放和生理反应之间的相互作用。
