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大鼠上涎核单位对鼓索神经刺激的反应。

Response of rat superior salivatory units to chorda tympani stimulation.

作者信息

Eisenman J S

出版信息

Brain Res Bull. 1983 Jun;10(6):811-5. doi: 10.1016/0361-9230(83)90213-7.

DOI:10.1016/0361-9230(83)90213-7
PMID:6311360
Abstract

Unit responses to chorda tympani stimulation in urethane anesthetized rats were characterized by response latency and frequency following ability. One hundred and fifty one units responded with constant latencies, mean: 16.9 msec, S.D.: 7.8 msec. Responses recorded from within the superior salivatory nucleus (SSN) had significantly longer latencies (18.8 +/- 6.8, n = 94) than those from surrounding areas (13.5 +/- 8.3, n = 50) (p less than 0.001). This difference was due to the higher incidence of responses with latencies between 2.7 and 10 msec outside of the SSN (44%) compared to SSN responses (8%). Ability to follow high frequency stimulation ranged from 2-550 Hz, and was the same for SSN neurons and those outside the nucleus. The population of responses localized to the SSN, with latencies greater than 10 msec and with high (greater than 100 Hz) frequency following, had a mean latency of 20.5 msec. The estimated conduction velocity for these presumed preganglionic, parasympathetic neurons is 0.85 M/sec +/- 0.25, significantly slower than that reported for similar responses in cats. The antidromic nature of these responses requires confirmation.

摘要

在氨基甲酸乙酯麻醉的大鼠中,鼓索神经刺激的单位反应以反应潜伏期和跟随高频刺激的能力为特征。151个单位以恒定潜伏期做出反应,平均潜伏期为16.9毫秒,标准差为7.8毫秒。从 superior salivatory nucleus(SSN)内记录到的反应潜伏期(18.8±6.8,n = 94)明显长于周围区域(13.5±8.3,n = 50)(p<0.001)。这种差异是由于SSN外潜伏期在2.7至10毫秒之间的反应发生率较高(44%),而SSN内反应发生率为8%。跟随高频刺激的能力范围为2 - 550赫兹,SSN神经元和核外神经元的该能力相同。定位到SSN的反应群体,潜伏期大于10毫秒且跟随高频(大于100赫兹)刺激,其平均潜伏期为20.5毫秒。这些假定的节前副交感神经元的估计传导速度为0.85米/秒±0.25,明显慢于猫中类似反应的报道速度。这些反应的逆向性需要证实。

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