Abeloff M D, Klastersky J, Drings P D, Eagan R T, Greco F A, Holsti L, Mattson K, Postmus P E
Cancer Treat Rep. 1983 Jan;67(1):21-6.
Improvements in therapy for small cell carcinoma of the lung have been achieved with treatment regimens that result in significant toxicity. The workshop of the International Association for the Study of Lung Cancer focused on the following complications of chemotherapy and radiotherapy: leukopenia and resultant infections, esophagitis, pneumonitis and pulmonary fibrosis, cardiac toxicity, second malignancies, neurologic complications, and psychosocial effects. The data regarding the incidence and management of these complications are briefly reviewed, and recommendations for further studies are noted.
通过具有显著毒性的治疗方案,肺癌小细胞癌的治疗已取得进展。国际肺癌研究协会研讨会聚焦于化疗和放疗的以下并发症:白细胞减少及由此引发的感染、食管炎、肺炎和肺纤维化、心脏毒性、第二原发恶性肿瘤、神经并发症以及社会心理影响。简要回顾了关于这些并发症的发生率及处理的数据,并指出了进一步研究的建议。