Hellsten S
Eur Urol. 1978;4(2):132-7. doi: 10.1159/000473930.
36 mongrels were subjected to splenic artery implantation into the left kidney. A stenosis of the left renal artery was created in 33 of the dogs. The revascularization process from the implanted artery was studied by angiography in vivo and ex vivo, by histological examination and by blood flow measurements. After creation of the stenosis and eventual occlusion of the left renal artery, newly formed intrarenal vessels could be demonstrated next to the implanted artery. These vessels formed communications between the splenic and intrarenal arteries. The experimental animals survived contralateral nephrectomy and ligature of the ipsilateral renal artery with a slight or moderate elevation of the serum creatinine level, provided that a slowly progressing stenosis of the renal artery was created.
36只杂种犬接受了脾动脉植入左肾的手术。33只犬制造了左肾动脉狭窄。通过体内和体外血管造影、组织学检查以及血流量测量，研究了植入动脉的血管重建过程。在制造左肾动脉狭窄并最终闭塞后，可在植入动脉旁显示新形成的肾内血管。这些血管在脾动脉和肾内动脉之间形成了交通。只要缓慢进展性肾动脉狭窄被制造出来，实验动物在对侧肾切除和同侧肾动脉结扎后存活，血清肌酐水平有轻微或中度升高。
