Fernandez J M, Ferrandiz M, Larrea L, Ramio R, Boada M
J Neurol Neurosurg Psychiatry. 1983 Sep;46(9):862-6. doi: 10.1136/jnnp.46.9.862.
In a case of cephalic tetanus with left facial spasms and trismus, the repetitive stimulation of the left facial nerve at 3, 10 and 20 Hz showed no facilitation or decrement. The amplitudes of the blink reflex were 50% lower on the affected side. The silent period of the masseter muscles was shortened. Concentric needle examination of the masseters and left facial EMG of the left frontalis muscle showed increased jitter and blocking in a significant proportion of the recorded potentials. Both jitter and blocking improved on higher innervation rates. All electrophysiological findings were normal on the second examination when the patient was asymptomatic. The single fibre EMG findings point to a presynaptic defect in the neuromuscular transmission in human tetanus.
在一例伴有左侧面部痉挛和牙关紧闭的头部破伤风病例中,以3、10和20赫兹频率重复刺激左侧面神经,未显示易化或递减现象。患侧瞬目反射的波幅降低了50%。咬肌的静息期缩短。对咬肌进行同心针电极检查以及对左侧额肌进行左侧面部肌电图检查显示,在记录到的电位中,相当一部分出现了抖动增加和阻滞现象。在较高的神经支配率下,抖动和阻滞现象均有所改善。当患者无症状时,第二次检查的所有电生理结果均正常。单纤维肌电图结果表明人类破伤风存在神经肌肉传递的突触前缺陷。