Linsey M, Smith W, Yamauchi H, Bernstein L
Laryngoscope. 1983 Oct;93(10):1328-31. doi: 10.1002/lary.1983.93.10.1328.
Unexplained osteomalacia may be the result of various neoplasma including ENT tumors. The mechanism of this oncogenic osteomalacia is uncertain, but it may result from a tumor-induced alteration in vitamin-D metabolism or from a direct phosphaturic action of a tumor product. Thorough ENT evaluation of patients presenting with unexplained osteomalacia is indicated, as successful tumor excision can lead to cure.
不明原因的骨软化症可能是包括耳鼻喉肿瘤在内的各种肿瘤的结果。这种致癌性骨软化症的机制尚不清楚,但可能是肿瘤引起的维生素D代谢改变或肿瘤产物的直接排磷作用所致。对于出现不明原因骨软化症的患者,有必要进行全面的耳鼻喉科评估,因为成功切除肿瘤可导致治愈。