光学活性儿茶酚咪唑啉在去大脑大鼠中的肾上腺素能受体介导效应 - Suppr

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Adrenoceptor-mediated effects of optically active catecholimidazolines in pithed rat.

作者信息

Ruffolo R R, Patil P N, Miller D D

出版信息

Naunyn Schmiedebergs Arch Pharmacol. 1983 Jul;323(3):221-7. doi: 10.1007/BF00497667.

DOI:10.1007/BF00497667

PMID:6312335

Abstract

摘要

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Adrenoceptor-mediated effects of optically active catecholimidazolines in pithed rat.光学活性儿茶酚咪唑啉在去大脑大鼠中的肾上腺素能受体介导效应

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Extrasynaptic location of alpha-2 and noninnervated beta-2 adrenoceptors in the vascular system of the pithed normotensive rat.α-2和无神经支配的β-2肾上腺素能受体在去脑正常血压大鼠血管系统中的突触外定位。

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Selectivity of some alpha adrenoceptor agonists for peripheral alpha-1 and alpha-2 adrenoceptors in the normotensive rat.正常血压大鼠中某些α肾上腺素能受体激动剂对外周α-1和α-2肾上腺素能受体的选择性

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Effect of aromatic fluorine substitution on the alpha and beta adrenoceptor-mediated effects of 3,4-dihydroxytolazoline in the pithed rat.芳香氟取代对脊髓麻醉大鼠中3,4-二羟基妥拉唑啉的α和β肾上腺素能受体介导作用的影响。

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Indications for vascular alpha- and beta-2 adrenoceptors in synapses of the muscarinic pathway in the pithed normotensive rat.去大脑正常血压大鼠毒蕈碱途径突触中血管α和β2肾上腺素能受体的指征

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Action of indoramin on pre- and postsynaptic alpha-adrenoceptors in pithed rats.

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Captopril impairs the vascular smooth muscle contraction mediated by postsynaptic alpha 2-adrenoceptors in the pithed rat.卡托普利可削弱去脑大鼠中由突触后α2肾上腺素能受体介导的血管平滑肌收缩。

Eur J Pharmacol. 1981 Sep 24;74(4):385-6. doi: 10.1016/0014-2999(81)90061-3.

引用本文的文献

Interaction of enantiomers of hydroxy tolazoline with adrenoceptors.羟基妥拉唑啉对映体与肾上腺素能受体的相互作用。

Naunyn Schmiedebergs Arch Pharmacol. 1987 Apr;335(4):391-6. doi: 10.1007/BF00165553.

Pharmacologic differentiation between pre- and postjunctional alpha 2-adrenoceptors by SK&F 104078.SK&F 104078对突触前和突触后α2-肾上腺素能受体的药理学区分

Naunyn Schmiedebergs Arch Pharmacol. 1987 Oct;336(4):415-8. doi: 10.1007/BF00164875.

Alpha-adrenoceptor activity of arylalkylimidazoles is improved by alpha-methylation and impaired by alpha-hydroxylation.

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本文引用的文献

Studies on the relationship between chemical constitution and physiological action: Molecular dissymmetry and physiological activity.化学组成与生理作用之间关系的研究：分子不对称性与生理活性。

Biochem J. 1933;27(4):1257-66. doi: 10.1042/bj0271257.

Action of local hormones: remarks on chemical specificity.

Proc R Soc Lond B Biol Sci. 1950 Oct 13;137(888):307-11. doi: 10.1098/rspb.1950.0041.

Stereochemical factors in biological activity.

Fortschr Arzneimittelforsch. 1959;1:455-530. doi: 10.1007/978-3-0348-7035-1_6.

Optically active catecholimidazolines: a study of steric interactions at alpha-adrenoreceptors.旋光性儿茶酚咪唑啉：α-肾上腺素能受体空间相互作用的研究

J Med Chem. 1983 Jul;26(7):957-63. doi: 10.1021/jm00361a005.

Differences in the applicability of the easson-stedman hypothesis to the alpha 1- and alpha 2-adrenergic effects of phenethylamines and imidazolines.伊登-斯特德曼假说对苯乙胺类和咪唑啉类药物α1-和α2-肾上腺素能效应适用性的差异。

Eur J Pharmacol. 1983 Jan 21;86(3-4):471-5. doi: 10.1016/0014-2999(83)90199-1.

Stereochemical requirements of alpha-2 adrenergic receptors.α-2肾上腺素能受体的立体化学要求

J Pharmacol Exp Ther. 1982 Sep;222(3):645-51.

J Pharmacol Exp Ther. 1982 Jun;221(3):762-8.

Vasoconstriction mediated by postsynaptic alpha 2-adrenoceptor stimulation.由突触后α2肾上腺素能受体刺激介导的血管收缩。

Naunyn Schmiedebergs Arch Pharmacol. 1980 Aug;313(1):17-20. doi: 10.1007/BF00505799.

Investigation into different types of post- and presynaptic alpha-adrenoceptors at cardiovascular sites in rats.大鼠心血管部位不同类型突触后和突触前α-肾上腺素能受体的研究。

Eur J Pharmacol. 1980 Aug 8;65(4):393-402. doi: 10.1016/0014-2999(80)90343-x.

Central cardiovascular alpha-adrenoceptors. Relation to peripheral receptors.

Circ Res. 1980 Jun;46(6 Pt 2):I21-5.

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