Mitchell R, Wilson L E
Neuropharmacology. 1983 Jul;22(7):935-8. doi: 10.1016/0028-3908(83)90145-4.
The effects of GABA agonists on [3H] flunitrazepam binding were examined in membranes from CNS areas proposed to contain different populations of benzodiazepine binding site subtypes (BZ1/BZ2). Since these effects were broadly similar in both cerebellar and hippocampal membranes, it seems unlikely that GABA receptors interacting with the proposed BZ1/BZ2 binding sites have markedly different properties. Sodium chloride clearly facilitated the potentiating effect of muscimol on [3H] flunitrazepam binding but produced a complex interaction with the effects of GABA itself and the partial agonist imidazoleacetic acid in the phosphate buffer system used.
在拟含有不同亚型苯二氮䓬结合位点（BZ1/BZ2）的中枢神经系统区域的膜中，研究了γ-氨基丁酸（GABA）激动剂对[³H]氟硝西泮结合的影响。由于这些作用在小脑和海马膜中大致相似，与拟BZ1/BZ2结合位点相互作用的GABA受体似乎不太可能具有明显不同的特性。氯化钠明显促进了蝇蕈醇对[³H]氟硝西泮结合的增强作用，但在所用的磷酸盐缓冲系统中，它与GABA本身及部分激动剂咪唑乙酸的作用产生了复杂的相互作用。
