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[头孢替安(SCE 963)临床活性评估。7个中心的多中心研究]

[Evaluation of the clinical activity of cefotiam (SCE 963). Multicentric study in 7 centers].

作者信息

Bryskier A, Humbert G, Borsa F, Bertrand A, Janbon F, Lafaix C, Beucler A, Veyssier P, Dusehu E, Modai J

出版信息

Pathol Biol (Paris). 1983 May;31(5):328-35.

PMID:6312392
Abstract

Cefotiam (SCE 963), a new, broad-spectrum, third generation cephalosporin was used in the treatment of 136 patients suffering from respiratory tract infections, urinary tract infections, septicemia, meningitis, biliary tract infections and osteoarthritis infections. Cefotiam was administered in monotherapy to 98 patients at the mean posology of two grams per day (extreme doses: 1 to 6 g). The following clinical effectiveness was noted: 83 successes and 18 failures on 101 available clinical reports. The general, biological tolerance and renal tolerance was good in all patients.

摘要

头孢替安(SCE 963),一种新型广谱第三代头孢菌素,用于治疗136例患有呼吸道感染、尿路感染、败血症、脑膜炎、胆道感染和骨关节炎感染的患者。98例患者采用头孢替安单药治疗,平均剂量为每日2克(极量:1至6克)。在101份可用临床报告中,观察到以下临床疗效:83例成功,18例失败。所有患者的一般情况、生物学耐受性和肾脏耐受性良好。

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