血管加压素增强去甲肾上腺素对环磷酸腺苷积累的刺激作用。
Vasopressin potentiates the stimulation of cyclic AMP accumulation by norepinephrine.
作者信息
Church A C
出版信息
Peptides. 1983 Mar-Apr;4(2):261-3. doi: 10.1016/0196-9781(83)90124-9.
PMID:6312437
Abstract
Vasopressin, a peptide that appears to enhance the consolidation process of memory was studied for its ability to stimulate the accumulation of cyclic AMP in slices of the mouse hippocampus. While vasopressin alone exhibited no effects in this system, it substantially potentiated the effects of norepinephrine. Such actions are discussed in reference to an endogenous brain vasopressin system, and they suggest a possible neuromodulator role for vasopressin.
摘要
血管加压素是一种似乎能增强记忆巩固过程的肽，对其刺激小鼠海马切片中环磷酸腺苷（cAMP）积累的能力进行了研究。虽然单独使用血管加压素在该系统中没有表现出作用，但它显著增强了去甲肾上腺素的作用。参照内源性脑内血管加压素系统对这些作用进行了讨论，它们提示血管加压素可能具有神经调节作用。
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