Donovan D T, Conley J
Ann Otol Rhinol Laryngol. 1983 Sep-Oct;92(5 Pt 1):491-5. doi: 10.1177/000348948309200517.
Adenoid cystic carcinoma is one of the most common malignancies of the minor salivary glands in the head and neck. However, adenoid cystic carcinoma of the larynx is very rare, with less than 75 cases reported in the literature. We present three cases of adenoid cystic carcinoma of the subglottic region with 6-year, 9-year, and 18-year follow-up, respectively. The literature on adenoid cystic carcinoma of the subglottic area is reviewed. Symptoms of long duration, slow progressive growth with tendency for local recurrence, and eventual development of pulmonary metastasis is common. Five-year survival statistics do not appear as relevant as 10- and 20-year survival rates in this entity because of the often slow but pernicious nature of adenoid cystic carcinoma of the subglottic area. Despite aggressive therapy, the disease often leads to the eventual death of the patient. In our series one patient died, and two patients are alive and free of disease. The evaluation, treatment, and clinical course of this disease is discussed.
腺样囊性癌是头颈部小唾液腺最常见的恶性肿瘤之一。然而，喉腺样囊性癌非常罕见，文献报道不足75例。我们报告3例声门下区腺样囊性癌病例，分别随访了6年、9年和18年。并对声门下区腺样囊性癌的文献进行了综述。病程长、生长缓慢且有局部复发倾向、最终发生肺转移是其常见症状。由于声门下区腺样囊性癌通常进展缓慢但具有危害性，5年生存率统计似乎不如10年和20年生存率相关。尽管采取了积极的治疗，该疾病仍常导致患者最终死亡。在我们的病例系列中，1例患者死亡，2例患者存活且无疾病。本文讨论了该疾病的评估、治疗及临床过程。
