Bogaerts Y, Van Der Straeten M, Tasson J, Pauwels R
Eur J Respir Dis. 1983 Oct;64(7):541-50.
Differentiating sarcoidosis from malignant neoplasms is not always easy. Sarcoidosis may present with bronchial stenosis and pseudotumorous formations in the lung and in various other organs. Conversely, metastatic or lymphomatous invasion of thoracic lymph nodes more often closely resembles the bilateral hilar adenopathies of sarcoidosis. Asymmetric lymph node swelling, while suggestive of malignancy, does not rule out sarcoidosis. Regional or generalised granuloma formation may occur in patients with malignant lymphoma or carcinoma of the lung, probably in reaction to neoplastic tissue. Its influence on prognosis remains obscure, but awareness of its possible presence is necessary in the diagnosis and staging of cancer. The present evidence does not indicate that sarcoidosis predisposes to malignant tumours.
鉴别结节病与恶性肿瘤并非总是易事。结节病可能表现为肺部及其他各种器官的支气管狭窄和假瘤形成。相反，胸内淋巴结的转移瘤或淋巴瘤浸润往往更类似于结节病的双侧肺门淋巴结肿大。不对称的淋巴结肿大虽提示恶性肿瘤，但不能排除结节病。恶性淋巴瘤或肺癌患者可能会出现局部或全身性肉芽肿形成，这可能是对肿瘤组织的反应。其对预后的影响尚不清楚，但在癌症的诊断和分期中，了解其可能存在是必要的。目前的证据并未表明结节病易引发恶性肿瘤。
