Fukuoka M, Takada M, Negoro S, Tamai S, Matsui K, Sakai N, Ryu S, Yoshinaga T
Gan No Rinsho. 1983 Aug;29(10):1223-8.
The influence of several factors for response to Chemotherapy and survival was analysed in 310 patients with inoperable lung cancer who were treated by single or combination chemotherapy. In small cell lung cancer, survival was strongly affected by the results of induction chemotherapy, and combination chemotherapy with three or four drugs was most effective. In non-small cell lung cancer, performance status and body weight loss on admission were important factors for response to chemotherapy and survival. Combinations did not improve the response rate in non-small cell lung cancer.
对310例无法手术的肺癌患者进行了单药或联合化疗，分析了几个因素对化疗反应和生存的影响。在小细胞肺癌中，诱导化疗结果对生存有强烈影响，三药或四药联合化疗最为有效。在非小细胞肺癌中，体能状态和入院时体重减轻是化疗反应和生存的重要因素。联合用药并未提高非小细胞肺癌的缓解率。
