通过与白蛋白和溶菌酶的相互作用判断氟处理羟基磷灰石的表面性质。

Surface properties of fluoride treated hydroxyapatite as judged by interactions with albumin and lysozyme.

作者信息

Eggen K H, Rölla G

出版信息

Scand J Dent Res. 1983 Oct;91(5):347-50. doi: 10.1111/j.1600-0722.1983.tb00828.x.

DOI:10.1111/j.1600-0722.1983.tb00828.x

Abstract

Hydroxyapatite treated with fluoride containing both alkali soluble fluoride (CaF2) and alkali stable fluoride (FAp) was shown to take up less albumin than hydroxyapatite but more lysozyme. The affinity of the adsorption of albumin to fluoride treated apatite was increased, whereas no difference was demonstrated in the affinity of lysozyme. Tooth surfaces in vivo contain both calcium fluoride and fluoroapatite. Protein adsorption to mixed phases may thus have clinical significance.

摘要

用含碱溶性氟化物（CaF₂）和碱稳定性氟化物（氟磷灰石）的氟化物处理的羟基磷灰石，与羟基磷灰石相比，显示出吸附的白蛋白较少，但溶菌酶较多。白蛋白对经氟化物处理的磷灰石的吸附亲和力增加，而溶菌酶的亲和力没有差异。体内牙齿表面同时含有氟化钙和氟磷灰石。因此，蛋白质对混合相的吸附可能具有临床意义。