Feldges A
Schweiz Med Wochenschr. 1983 Sep 10;113(36):1285-8.
Cancer is a rare disease in children, in whom some 200 new cases are recorded every year in Switzerland including about 20 in the eastern part of the country. In contrast to cancer in adults, many malignancies of the child have prospects of cure. This improved prognosis is mainly the result of interdisciplinary cooperation within the framework of controlled national and international protocols. Progress in the treatment of two representative forms of cancer (acute lymphocytic leukemia and Wilms tumor) is illustrated. 50% of all children from the eastern part of Switzerland with acute lymphocytic leukemia and 70% of those with Wilms tumor have been cured in the past 7 years. These impressive advances are unfortunately overshadowed by late sequelae of the therapy, which are described and must be taken into account in future therapeutic approaches.
癌症在儿童中是一种罕见疾病，在瑞士，每年约有200例新病例被记录，其中该国东部约有20例。与成人癌症不同，儿童的许多恶性肿瘤有治愈的前景。这种改善的预后主要是在国家和国际可控方案框架内跨学科合作的结果。文中阐述了两种代表性癌症（急性淋巴细胞白血病和肾母细胞瘤）治疗方面的进展。在过去7年中，瑞士东部所有患急性淋巴细胞白血病的儿童中有50%被治愈，患肾母细胞瘤的儿童中有70%被治愈。不幸的是，这些令人瞩目的进展被治疗的晚期后遗症所掩盖，文中对这些后遗症进行了描述，并且在未来的治疗方法中必须予以考虑。
