Turpin G, Heshmati H M, Darbois R, de Gennes J L
Sem Hop. 1983 Sep 29;59(34):2369-72.
Chronic hydrocephalus by aqueductal stenosis may result in endocrine dysfunction. Primary or secondary amenorrhea may be the only symptom. Endocrine function tests are usually normal, except for low estrogen levels, pointing to isolated functional hypothalamic amenorrhea. Roentgenologic investigations ensure diagnosis in all cases: skull films show enlargement and/or flattening of the sella turcica and digitate impressions; computed tomography shows dilatation of lateral and third ventricles. This rare cause of amenorrhea must be kept in mind as it can be easily diagnosed and successfully treated by atrioventricular shunt.
导水管狭窄所致的慢性脑积水可能导致内分泌功能障碍。原发性或继发性闭经可能是唯一症状。内分泌功能检查通常正常,仅雌激素水平较低,提示为孤立性功能性下丘脑闭经。放射学检查可确诊所有病例:颅骨平片显示蝶鞍增大和/或变平以及指压痕;计算机断层扫描显示侧脑室和第三脑室扩张。这种罕见的闭经原因必须牢记,因为它可以通过房室分流术轻松诊断并成功治疗。