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[肝脏糖原磷酸化酶的激素活性调控,特别涉及其在应激反应范围内的意义]

[Hormonal activity control of liver glycogen phosphorylases with special reference to their significance within the scope of a stress reaction].

作者信息

Németh S

出版信息

Z Gesamte Inn Med. 1983 Aug 1;38(15):405-8.

PMID:6314684
Abstract

For the mechanism of glycogen metabolism in the liver hormonal action of epinephrine, norepinephrine, glucagon, vasopressin and angiotensin II is of importance. The potential importance of hormonal regulation for interpreting the changes in glycogen metabolism under conditions of stress is underlined. Own results show an acute increase of glycogen phosphorylase activity in stress within 1-2 minutes. 24 hours fasting decreases the sensibility of this enzyme towards the hormonal influence.

摘要

对于肝脏中糖原代谢的机制而言,肾上腺素、去甲肾上腺素、胰高血糖素、血管加压素和血管紧张素II的激素作用至关重要。强调了激素调节在解释应激状态下糖原代谢变化方面的潜在重要性。自身研究结果表明,在应激状态下,糖原磷酸化酶活性在1 - 2分钟内会急剧增加。禁食24小时会降低该酶对激素影响的敏感性。

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