The digitalis glycosides are potent cardiovascular drugs with a low therapeutic index and a high incidence of iatrogenic complications. Digoxin is the most commonly used preparation. Common indications include rate control in atrial fibrillation, as well as the treatment of other atrial tachyarrhythmias, and low-output congestive heart failure. Digitalis is contraindicated in idiopathic hypertrophic subaortic stenosis (unless atrial fibrillation is present) and in some patients with Wolff-Parkinson-White syndrome.
洋地黄苷类是强效心血管药物,治疗指数低,医源性并发症发生率高。地高辛是最常用的制剂。常见适应证包括控制房颤的心率,以及治疗其他房性快速心律失常和低输出量性充血性心力衰竭。洋地黄在特发性肥厚性主动脉瓣下狭窄(除非存在房颤)和一些 Wolff-Parkinson-White 综合征患者中禁用。