Bazian A S, Brodskiĭ B L
Biofizika. 1983 Sep-Oct;28(5):858-62.
A mathematical model quantitatively describing the value of secreted mediator per each successive impulse in the series of presynaptic impulses is presented. The model is plotted with the account taken of the role of presynaptic adrenoreceptors regulating noradrenaline secretion. It has been shown that a decrease observed in neurophysiological experiments and further stabilization of postsynaptic responses in the series of presynaptic impulses of given frequency are not connected with a decreased content of noradrenaline in nerve endings, but may be connected with the work of presynaptic alpha and beta adrenoreceptors.
提出了一个数学模型，该模型定量描述了在一系列突触前冲动中，每一个连续冲动所分泌介质的量值。绘制该模型时考虑了调节去甲肾上腺素分泌的突触前肾上腺素能受体的作用。结果表明，在神经生理学实验中观察到的给定频率的突触前冲动系列中突触后反应的下降及进一步稳定，与神经末梢中去甲肾上腺素含量的减少无关，而可能与突触前α和β肾上腺素能受体的作用有关。
