Smith A W, Skilling D E, Ridgway S H, Fenner C A
J Am Vet Med Assoc. 1983 Dec 1;183(11):1219-22.
Tattoo lesions linked to the cetacean poxvirus of bottlenose dolphins regressed without treatment. Two types of regression were observed: (1) The tattoo lesions became raised and blanched, then disappeared along with sloughing skin. (2) When an incision was made through a tattoo lesion, the tattoo disappeared in a zone around the incision. Poxviruses removed from the raised, blanched skin lesions and from typical tattoo lesions were reacted with dolphin serums and examined by immunoelectron microscopy. Antibody was not detected against either of these poxvirus preparations when the dolphins had only typical tattoo lesions. However, after the raised, blanched lesions appeared, serums obtained during the acute or convalescent stages were positive for the poxvirus separated from the lesions. Regression of the typical tattoo lesions was concurrent with antibody conversion.
与宽吻海豚的鲸痘病毒相关的纹身损伤未经治疗便消退了。观察到两种消退类型：（1）纹身损伤隆起、变白，然后随着皮肤脱落而消失。（2）当在纹身损伤处切开时，纹身会在切口周围的区域消失。从隆起、变白的皮肤损伤和典型纹身损伤中分离出的痘病毒与海豚血清反应，并通过免疫电子显微镜检查。当海豚只有典型纹身损伤时，未检测到针对这两种痘病毒制剂的抗体。然而，在隆起、变白的损伤出现后，在急性期或恢复期获得的血清对从损伤中分离出的痘病毒呈阳性反应。典型纹身损伤的消退与抗体转化同时发生。
