Beer G M, Neuwirth A
Laryngol Rhinol Otol (Stuttg). 1983 Oct;62(10):468-70.
Necrotizing sialometaplasia, being a rare, nonspecific reaction to ischaemic injury in salivary gland tissues of the head, is discussed in connection with a case of our own. In contrast to former reports concerning such lesions above all in minor salivary glands the following report concentrates on a case of necrotizing sialometaplasia in the submaxillary salivary gland of a 57-year old woman who noticed after exstirpation of a pleomorphic adenoma in the submaxillary gland a swelling that presented histologically as necrotizing sialometaplasia. Emphasis is placed on a detailed morphological knowledge of this innocuous, self-repairing process, since the extensive squamous cell metaplasia of minor excretory ducts as the essential finding could be easily misdiagnosed as a squamous cell carcinoma and, therefore deserves special consideration in differential diagnosis of salivary gland tumours.
坏死性涎腺化生是一种罕见的、发生于头颈部唾液腺组织缺血性损伤的非特异性反应，本文结合我们自身的一个病例对此进行讨论。与以往关于此类病变的报道不同，以往报道主要集中在小唾液腺，而本报道聚焦于一名57岁女性下颌下唾液腺的坏死性涎腺化生病例。该女性在切除下颌下腺多形性腺瘤后发现肿胀，组织学检查显示为坏死性涎腺化生。重点强调对这一良性、可自愈过程的详细形态学认识，因为小排泄导管广泛的鳞状上皮化生这一关键表现很容易被误诊为鳞状细胞癌，因此在唾液腺肿瘤的鉴别诊断中值得特别关注。
