Crippa P R, Mazzini A
Physiol Chem Phys Med NMR. 1983;15(1):51-6.
The reactions of oxidation of NADH by Dopa and Dopamine-melanins show inhibition with low quantities of Superoxide dismutase, the enzyme which catalyzes the reaction: O2- + O2- + 2H+ leads to H2O2 + O2 and which has been used as an indicator of the involvement of superoxide ions in many biochemical systems. The reaction was also investigated in the presence of metal ions (Cu2, Zn2+ and Co2+) that are able to increase the extent of oxidation, and also in this case the inhibition effect of superoxide dismutase was observed. The results are interpreted in terms of a single electron pathway involving the superoxide ion and NAD.
多巴和多巴胺黑色素对NADH的氧化反应在加入少量超氧化物歧化酶时会受到抑制，该酶催化反应：O2- + O2- + 2H+ → H2O2 + O2，并且已被用作超氧离子参与许多生化系统的指标。还研究了在能够增加氧化程度的金属离子（Cu2+、Zn2+和Co2+）存在下的反应，在这种情况下也观察到了超氧化物歧化酶的抑制作用。结果根据涉及超氧离子和NAD的单电子途径进行解释。
