Vison N, Hecketsweiler P, Butel J, Bernier J J
Gut. 1978 Mar;19(3):194-8. doi: 10.1136/gut.19.3.194.
Pancreatic secretion of lipase and chymotrypsin in response to elemental diets and a crushed food homogenate was studied in normal subjects. The solutions were infused at constant flow rates at the ligament of Treitz with polyethylene glycol as a nonabsorbable marker. A triple lumen tube was used, enabling collection of secretions at 35 and 70 cm from the infusion point. The results show that a crushed food homogenate has a greater stimulative effect on pancreatic enzyme secretion than the elemental solutions and that this can be directly related to its greater nitrogen content. The osmolality of the infused solutions does not appear to be important. The relative merits of the solutions tested and total parental nutrition in reducing pancreatic enzyme secretion are discussed.
在正常受试者中研究了胰腺对要素饮食和粉碎食物匀浆的脂肪酶和胰凝乳蛋白酶分泌反应。溶液以恒定流速在屈氏韧带处输注，使用聚乙二醇作为不可吸收标记物。使用三腔管，能够在距输注点35和70厘米处收集分泌物。结果表明，粉碎食物匀浆对胰腺酶分泌的刺激作用比要素溶液更大，这可能与其更高的氮含量直接相关。输注溶液的渗透压似乎并不重要。讨论了所测试溶液和全胃肠外营养在减少胰腺酶分泌方面的相对优点。
