Kuhn E, Fiehn W
Fortschr Med. 1978 Mar 23;96(11):577-80.
Serum insulin levels were determined in patients with myotonic dystrophy after intravenous administration of glucose and were found to be higher than in control persons in about 60%. Although several interpretations of this observation are possible we favor the assumption, that an increased sensitivity of the insulin producing system of the pancreas is the reason. With regard to the most accepted hypothesis that myotonic dystrophy is a disorder due to impaired membrane function, it is tempting to explain our findings by an altered membranal function of the insulin producing cells, too.
在静脉注射葡萄糖后，对强直性肌营养不良患者的血清胰岛素水平进行了测定，发现约60%的患者血清胰岛素水平高于对照组。尽管对这一观察结果有几种可能的解释，但我们倾向于认为，胰腺胰岛素分泌系统敏感性增加是原因所在。关于最被认可的假说，即强直性肌营养不良是一种由于膜功能受损导致的疾病，也很容易用胰岛素分泌细胞的膜功能改变来解释我们的发现。
