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先天性肌病中的胞质体可用抗结蛋白（一种肌肉特异性中间丝蛋白）抗体进行染色。

The cytoplasmic bodies in a congenital myopathy can be stained with antibodies to desmin, the muscle-specific intermediate filament protein.

作者信息

Osborn M, Goebel H H

出版信息

Acta Neuropathol. 1983;62(1-2):149-52. doi: 10.1007/BF00684933.

DOI:10.1007/BF00684933
PMID:6318501
Abstract

Cytoplasmic bodies found in a muscle biopsy from a 14-year-old girl afflicted with a lifelong congenital myopathy reveal an electron-dense core surrounded by 7-10 nm filaments. Typing of the kind of intermediate filaments present shows that they are of the desmin type.

摘要

在一名患有先天性肌病的14岁女孩的肌肉活检中发现的胞质体显示，其电子致密核心被7-10纳米的细丝包围。对存在的中间丝类型进行分类表明它们是结蛋白类型。

相似文献

1
The cytoplasmic bodies in a congenital myopathy can be stained with antibodies to desmin, the muscle-specific intermediate filament protein.先天性肌病中的胞质体可用抗结蛋白（一种肌肉特异性中间丝蛋白）抗体进行染色。
Acta Neuropathol. 1983;62(1-2):149-52. doi: 10.1007/BF00684933.
2
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3
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Familial desminopathy: myopathy with accumulation of desmin-type intermediate filaments.家族性结蛋白病：伴有结蛋白型中间丝聚集的肌病。
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引用本文的文献

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本文引用的文献

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Differentiation-related patterns of expression of proteins of intermediate-size filaments in tissues and cultured cells.组织和培养细胞中中等大小中间丝蛋白的分化相关表达模式。
Cold Spring Harb Symp Quant Biol. 1982;46 Pt 1:431-53. doi: 10.1101/sqb.1982.046.01.041.
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Heterogeneity of intermediate filament expression in vascular smooth muscle: a gradient in desmin positive cells from the rat aortic arch to the level of the arteria iliaca communis.血管平滑肌中间丝表达的异质性：从大鼠主动脉弓到髂总动脉水平，结蛋白阳性细胞呈梯度变化。
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Neuromuscul Disord. 2017 Jun;27(6):531-536. doi: 10.1016/j.nmd.2017.02.012. Epub 2017 Mar 2.
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Congenital myopathies.先天性肌病
Brain Pathol. 2001 Apr;11(2):206-17. doi: 10.1111/j.1750-3639.2001.tb00393.x.
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Stress-response proteins in cardiovascular disease.心血管疾病中的应激反应蛋白。
Am J Hum Genet. 1999 Mar;64(3):685-90. doi: 10.1086/302305.
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Hereditary myopathy of the diaphragmatic muscles in Holstein-Friesian cattle.
Acta Neuropathol. 1995;90(4):339-46. doi: 10.1007/BF00315007.
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Experimental emetine myopathy: enzyme histochemical, electron microscopic, and immunomorphological studies.
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Intermediate-size filaments: changes in synthesis and distribution in cells of the myogenic and neurogenic lineages.
中等大小丝：肌源性和神经源性谱系细胞中合成与分布的变化
Cold Spring Harb Symp Quant Biol. 1982;46 Pt 1:317-29. doi: 10.1101/sqb.1982.046.01.033.
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An unusual familial cardiomyopathy characterized by aberrant accumulations of desmin-type intermediate filaments.一种罕见的家族性心肌病，其特征为结蛋白型中间丝异常聚集。
Virchows Arch A Pathol Anat Histol. 1981;393(1):53-60. doi: 10.1007/BF00430870.
5
Mallory body-like inclusions in a hereditary congenital neuromuscular disease.遗传性先天性神经肌肉疾病中的马洛里小体样包涵体。
Muscle Nerve. 1983 Mar-Apr;6(3):195-200. doi: 10.1002/mus.880060305.
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Congenital myopathy with cytoplasmic bodies.
Neuropediatrics. 1981 May;12(2):166-80. doi: 10.1055/s-2008-1059649.
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A new type of hereditary distal myopathy with characteristic sarcoplasmic bodies and intermediate (skeletin) filaments.一种新型的遗传性远端肌病，具有特征性的肌浆体和中间（骨骼素）细丝。
J Neurol Sci. 1980 Aug;47(2):171-90. doi: 10.1016/0022-510x(80)90002-7.
8
The amino acid sequence of chicken muscle desmin provides a common structural model for intermediate filament proteins.鸡肌肉结蛋白的氨基酸序列为中间丝蛋白提供了一个通用的结构模型。
EMBO J. 1982;1(12):1649-56. doi: 10.1002/j.1460-2075.1982.tb01368.x.
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Tumor diagnosis by intermediate filament typing: a novel tool for surgical pathology.通过中间丝分型进行肿瘤诊断：外科病理学的一种新工具。
Lab Invest. 1983 Apr;48(4):372-94.
10
Intermediate filaments.中间丝
Cold Spring Harb Symp Quant Biol. 1982;46 Pt 1:413-29. doi: 10.1101/sqb.1982.046.01.040.