Citron M L, Krasnow S H, Grant C, Cohen M H
Arch Intern Med. 1984 Jan;144(1):177.
A 53-year-old man with small-cell lung carcinoma underwent bone marrow aspirations and biopsies for tumor staging and harvest for autologous bone marrow infusion. Fourteen months after bone marrow aspiration and biopsy, a subcutaneous lesion grew over the posterior iliac crest, and a biopsy specimen disclosed small-cell carcinoma. To our knowledge, this is the first case report of tumor seeding associated with bone marrow aspirate and biopsy.
一名53岁的小细胞肺癌男性患者接受了骨髓穿刺和活检,以进行肿瘤分期并采集自体骨髓用于输注。骨髓穿刺和活检14个月后,右侧髂嵴后方出现一个皮下肿物,活检标本显示为小细胞癌。据我们所知,这是首例与骨髓穿刺和活检相关的肿瘤种植的病例报告。