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[自发性高血压大鼠血液和肺组织中的血管紧张素转换酶活性]

[Angiotensin converting enzyme activity in the blood and lung tissue of spontaneously hypertensive rats].

作者信息

Komissarova N V, Gomazkov O A, Karpitskiĭ V V

出版信息

Biull Eksp Biol Med. 1983 Dec;96(12):30-2.

PMID:6318853
Abstract

Angiotensin-converting enzyme (ACE) activity in blood serum and lung tissue was studied in spontaneously hypertensive rats. ACE activity in blood serum and lung tissue in normotensive and spontaneously hypertensive rats (SHR) was significantly different. In normotensive rats (NTR), ACE activity in serum was much higher than in SHR. In the lung tissue, the differences were less marked. During ontogenetic development, NTR demonstrated a decrease in ACE activity in serum and an increase in lung tissue, while SHR showed the total decrease in the enzyme activity.

摘要

在自发性高血压大鼠中研究了血清和肺组织中的血管紧张素转换酶(ACE)活性。正常血压大鼠和自发性高血压大鼠(SHR)血清和肺组织中的ACE活性存在显著差异。在正常血压大鼠(NTR)中,血清中的ACE活性远高于SHR。在肺组织中,差异不太明显。在个体发育过程中,NTR血清中的ACE活性降低,肺组织中的ACE活性增加,而SHR则显示该酶活性总体下降。

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