血型物质H和癌胚抗原在结直肠癌中的分布

The distribution of blood group substance H and CEA in colorectal carcinoma.

作者信息

Schoentag R, Williams V, Kuhns W

出版信息

Cancer. 1984 Feb 1;53(3):503-9. doi: 10.1002/1097-0142(19840201)53:3<503::aid-cncr2820530323>3.0.co;2-j.

DOI:10.1002/1097-0142(19840201)53:3<503::aid-cncr2820530323>3.0.co;2-j

Abstract

The distributional patterns of blood group substance H and carcinoembryonic antigen (CEA) in 20 colorectal carcinomas from 17 patients, were investigated. Prognosis in these cases was more obviously related to histologic classification and pathologic stage than to BGS and CEA distributional patterns or preoperative plasma CEA levels. The distribution of H and CEA was similar to that found by other investigators for A and B blood group substances with the exception that areas of identical localization could be shown in at least some areas of each tumor studied that was positive for both antigens. The relationship of CEA and BGS is as yet unknown, but it seems probable that they can occur simultaneously in the same tissue.

摘要

对17例患者的20例结肠直肠癌中血型物质H和癌胚抗原（CEA）的分布模式进行了研究。这些病例的预后与组织学分类和病理分期的关系比与血型物质（BGS）和CEA分布模式或术前血浆CEA水平的关系更为明显。H和CEA的分布与其他研究者在A和B血型物质中发现的分布相似，不同之处在于，在所研究的每个肿瘤的至少一些区域中，可以显示出两种抗原均呈阳性的相同定位区域。CEA和BGS之间的关系尚不清楚，但它们似乎有可能在同一组织中同时出现。